[Remote] Senior Information Security Engineer – Endpoint Engineer

Note: The job is a remote job and is open to candidates in USA. UChicago Medicine is a world-class academic healthcare system, and they are seeking a Senior Information Security Engineer in their Information Security department. This role will lead efforts to enhance and mature the defensible architecture across network and Cloud solutions, assist in Incident Response, and create Standard Operating Procedures for SOC operations related to Network Security solutions. Responsibilities • Primary subject matter expert for all Endpoint Security related functions • Deploy, configure, and manage Endpoint Detection and Response (EDR) solutions (e.g., CrowdStrike, Microsoft Defender ATP, SentinelOne) • Design and maintain endpoint security architectures (Windows, Mac, Linux) • Assist other security engineering and consulting needs as they arise • Develop project plans and manage project teams for security related projects • Provide communications, including status reporting, risk management, escalation of issues, and in general, making sure the project is delivered on budget, on schedule, and within scope • Other duties as assigned Skills • BS or BA degree in Computer Science or other IT related field, or combination of education and work experience • 8 years of Information Security experience required, preferably at least 3 years in a Senior or Lead Engineering role • 5 years' experience maintaining and designing Defense-in-Depth strategies for complex network architectures • Proficiency in deploying, configuring, and troubleshooting EDR and AV solutions • Effective written and verbal communication skills • Good working knowledge of the Plan, Build, Run model within an IT environment • Expert understanding of TCP/IP (OSI Layers 1– 4) and Internet and Intranet technologies required (OSI Layers 5-7) • Good knowledge of Windows and Linux Operating Systems • Some scripting or programming skills (PERL, Python, PowerShell, etc.) preferred as needed • Good knowledge of vulnerability management, risk analysis, and forensics preferred • Experience with HIPAA, NIST, FERPA, and SOX preferred Benefits • Medical and religious exemptions will be considered for flu vaccination consistent with applicable law. Company Overview • The University of Chicago Medicine has been at the forefront of medicine since 1927, when we cared for our first patients. It was founded in 1927, and is headquartered in Chicago, Illinois, USA, with a workforce of 5001-10000 employees. Its website is Company H1B Sponsorship • UChicago Medicine has a track record of offering H1B sponsorships, with 38 in 2025, 31 in 2024, 28 in 2023, 17 in 2022, 23 in 2021, 17 in 2020. Please note that this does not guarantee sponsorship for this specific role. Apply tot his job